Proton NMR imaging of cerebral blood flow using H2(17)O. |
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| Authors: | K K Kwong A L Hopkins J W Belliveau D A Chesler L M Porkka R C McKinstry D A Finelli G J Hunter J B Moore R G Barr |
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| Affiliation: | Department of Radiology, Massachusetts General Hospital, Charlestown 02129. |
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| Abstract: | Cerebral blood flow was quantitatively mapped by monitoring the cerebral washout of H2(17)O using rapid, single-shot proton NMR imaging. H2(17)O acts as a freely diffusible contrast agent for proton imaging via its scalar-coupled term, enhancing T2 relaxation. Measured values for CBF ranged from 29 to 106 ml/min/100 g over a range of arterial pCO2 between 23 and 81 Torr. |
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