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鹅绒委陵菜化学成分及药理作用研究进展
引用本文:刘意,成亮,延在昊,何泉泉,孔德云.鹅绒委陵菜化学成分及药理作用研究进展[J].中草药,2015,46(8):1251-1258.
作者姓名:刘意  成亮  延在昊  何泉泉  孔德云
作者单位:上海医药工业研究院 创新药物与制药工艺国家重点实验室, 上海 200040;上海医药工业研究院 创新药物与制药工艺国家重点实验室, 上海 200040;爱茉莉太平洋(上海)研发有限公司, 上海 201801;爱茉莉太平洋(上海)研发有限公司, 上海 201801;上海医药工业研究院 创新药物与制药工艺国家重点实验室, 上海 200040
摘    要:蕨麻作为药食两用植物,已有1 200多年的药用历史.蕨麻为鹅绒委陵菜Potentilla anserina的膨大的块根,鹅绒委陵菜化学成分研究发现其主要含有三萜、皂苷和黄酮类成分.近年来药理学研究发现其具有抗缺氧、抗氧化、保肝、增强免疫力等作用.现对鹅绒委陵菜化学成分和药理作用研究进展进行综述,以期为其深入开发利用提供参考.

关 键 词:鹅绒委陵菜  三萜  皂苷  黄酮  抗缺氧  抗氧化  保肝
收稿时间:2014/9/15 0:00:00

Research progress on chemical constituents from Potentilla anserina and their pharmacological activities
LIU Yi,CHENG Liang,YEON Jae-ho,HE Quan-quan and KONG De-yun.Research progress on chemical constituents from Potentilla anserina and their pharmacological activities[J].Chinese Traditional and Herbal Drugs,2015,46(8):1251-1258.
Authors:LIU Yi  CHENG Liang  YEON Jae-ho  HE Quan-quan and KONG De-yun
Institution:State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China;State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China;Amorepacific Shanghai R&I Center, Shanghai 201801, China;Amorepacific Shanghai R&I Center, Shanghai 201801, China;State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China
Abstract:Potentilla Anserinae Radix used as both food and medicine over 1 200 years is the root tubers of Potentilla anserine. Triterpenoids, saponins, and flavonoids are the main chemical constituents in P. anserine. P. anserine shows the activities of anti-hypoxia, antioxidation, liver-protection, and enhancement of immunity in the recent studies. In this paper, the chemical constituents from P. anserine and their pharmacological activities are reviewed, which could provide the reference for the further investigation and development of this plant.
Keywords:Potentilla anserine L    triterpenoids  saponins  flavonoids  antihypoxia  anti-oxidation  liver-protection
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