Lupus anticoagulant as a marker of autoimmunity in recurrent pregnancy loss; a case report |
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Authors: | J Balasch A López-Soto J Font B Puerto |
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Institution: | Department of Obstetrics and Gynecology, Faculty of Medicine, Hospital Clinic i Provincial, Barcelona, Spain. |
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Abstract: | We present a patient with primary antiphospholipid syndrome, as defined by nine pregnancy losses, the presence of lupus anticoagulant (LAC), and the absence of clinical signs and symptoms of autoimmunity. A successful pregnancy was achieved by treatment with low-dose prednisone (15 mg daily) and aspirin (100 mg daily). The patient was followed-up throughout her two last pregnancies and a 6 months postpartum period. Our data indicate that LAC serves as a marker of disease in women with previous pregnancy wastages, and that aspirin-prednisone therapy is beneficial in carefully selected patients. |
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