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补阳还五汤治疗缺血性中风药理作用机制的研究进展
引用本文:龙建飞,张秋霞,王蕾,赵晖,张楠. 补阳还五汤治疗缺血性中风药理作用机制的研究进展[J]. 世界中医药, 2015, 10(5)
作者姓名:龙建飞  张秋霞  王蕾  赵晖  张楠
作者单位:首都医科大学中医药学院,北京,100069
基金项目:北京市属高等学校人才强教深化计划“中青年骨干人材培养计划”项目(编号:PXM2011014226)
摘    要:近年来,国内学者对补阳还五汤抗脑缺血的药理作用进行了大量研究,结果表明:补阳还五汤可通过改善血液流变性、提高脑组织能量代谢、抗炎、抗自由基损伤、保护血脑屏障,促进神经发生、保护神经元等多种途径抗脑缺血损伤。文章就补阳还五汤治疗缺血性中风药理作用机制作一综述。

关 键 词:补阳还五汤;脑缺血;神经保护;凋亡
收稿时间:2014-04-03

Research Progress of Pharmacological Mechanism of Buyang Huanwu Decoction in Ischemic Apoplexy
Long Jianfei,Zhang Qiuxi,Wang Lei,Zhao Hui,Zhang Nan. Research Progress of Pharmacological Mechanism of Buyang Huanwu Decoction in Ischemic Apoplexy[J]. World Chinese Medicine, 2015, 10(5)
Authors:Long Jianfei  Zhang Qiuxi  Wang Lei  Zhao Hui  Zhang Nan
Abstract:In recent years, domestic scholars have conducted a lot of researches on the pharmacological effects of Buyang Huanwu Decoction(BYHWD) against the cerebral ischemia. The results showed that BYHWD could regulate cerebral hemodynamics factors, it was anti-inflammatory, against free radicals, and could protect the blood-brain barrier and neurons against the cerebral ischemic injury. This paper reviewed the pharmacological mechanism of BYHWD in treatment of ischemic stroke.
Keywords:Buyang Huanwu decoction   Cerebral ischemia   Neuroprotection   Apoptosis
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