Leucocyte variation, an insight of host defenses during hymenolepiasis and restoration with praziquantel

Haematological studies in helminthiasis reveal drastic alterations in the white blood cells (leucocytes), and its various components like neutrophils, lymphocytes, monocytes and eosinophils. The use of proper anthelmintic agent, restores normalcy in the infected host. These variations during helminth infections reflect the host defense status in combating the parasitic attack. The present study involves the evaluation of these total and differential haematological alterations, induced in the laboratory mouse Mus musculus, infested with the intestinal helminth, Hymenolepis nana (dwarf tapeworm), and treated with the praziquantel, using an automatic Coulter Counter.