胸腺瘤合并重症肌无力的治疗

报告32例胸腺瘤合并重症肌无力的治疗（包括术前准备、手术方法、术后药物治疗）.32例不同分期的胸腺瘤,30例采用胸正中切口或胸正中切口＋颈部切口,两例采用后外侧＋胸正中切口.除眼肌型外,术前均给予免疫球蛋白及甲泼尼龙冲击治疗.结论：胸正中切口或胸正中切口＋颈部切口可以充分切除胸腺组织,术前给予抗胆碱脂酶药物＋皮质类固醇类药物及免疫球蛋白能明显降低重症肌无力危象的发生.术后合理应用抗胆碱脂酶药物和及时气管切开是抢救成功的关键.

Treatment of thymoma with myasthenia gravis

Aim：Summary report 32 cases of thymoma with myasthenia gravis（including preoperative preparation,surgical technique,postoperative medication therapy）.32 patients with different stages of thymoma,30 cases have adopted the median splitting stermotomy or cervi-thoraco two incision.two cases have adopted the posterior lateral ＋ median splitting stermotomy.In addition to ocular,the patients were given immune globulin before operation and methylprednisolone pulse therapy.Conclusion： thymus can be fully removed with the median splitting stermotomy or cervi-thoraco two incision.preoperative anti-cholinesterase drugs,corticosteroids and immunoglobulin can significantly reduce the occurrence of myasthenia crisis.postoperative reasonable application of anti-cholinesterase drugs and timely tracheotomy is the key to successful treatment.