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The effect of zinc deficiency on the ultrastructure of rat adrenal cortex
Authors:Alphonse E. Leure Dupree  Richard J. Rothman  Gary J. Fosmire
Abstract:The adrenal cortex of male Sprague-Dawley weanling rats maintained on a zinc-deficient diet was studied by electron microscopy. There was a gradual increase in lipid droplets in the zona fasciculata which was quite marked at 7 weeks, but increased lipid was not observed in the zona glomerulosa or reticularis of zinc-deficient rats. The adrenal cortex of the control animals did not show altered lipid content. A possible explanation for the effect of zinc deficiency on the adrenal cortex is offered.
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