前列腺液IL-6、IL-8在诊断BPH合并CP的临床意义

目的探讨前列腺液(EPS)内IL-6(白细胞介素6)、IL-8浓度水平对区分单纯良性前列腺增生(BPH)和BPH合并慢性前列腺炎(CP)的意义。方法 100例前列腺手术的BPH病人,在术前行前列腺液IL-6、IL-8浓度检测。术中取前列腺组织标本,根据病理前列腺炎诊断标准确定单纯BPH患者与BPH合并CP患者。结果 BPH合并CP病人EPS中IL-6、L-8浓度较单纯BPH病人明显升高(P<0.01或P<0.05)。结论 EPS中IL-6、IL-8浓度水平与BPH患者是否伴发CP的关系密切,二者在区别单纯BPH与BPH合并CP时具有较高价值。

The clinical significance of IL-6 and IL-8 in EPS in diagnosis of BPH with chronic prostatitis

Objective To investigate the significance that the concentration levels change of IL-6 and IL-8 in EPS were used to distinguish simple BPH and BPH with chronic prostatitis.Methods Patients with BPH who needed prostate surgery could through prostatic massage to get EPS before surgery,then the Concentration of IL-6 and IL-8 were measured.The prostate tissue specimens were Collected in surgery,according to the pathological prostatitis diagnosis standard to confirm research object of patients who had simple BPH and BPH with chronic prostatitis.Results The IL-6 and IL-8 in EPS which BPH with chronic prostatitis expressed was higher than simple BPH.Conclusion The Concentration levels of IL-6 and IL-8 in EPS which were close to patients whether BPH with chronic prostatitis were more effective to distinguish simple BPH and BPH with chronic prostatitis.