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巯甲丙脯酸,尼群地平对高血压左室肥厚逆转作用的疗效比较
引用本文:窦学荣 李金龙. 巯甲丙脯酸,尼群地平对高血压左室肥厚逆转作用的疗效比较[J]. 泰山医学院学报, 2000, 21(1): 32-33
作者姓名:窦学荣 李金龙
作者单位:山东省泰山慢性病医院!山东泰安271000(窦学荣,孟庆华),泰安市中心医院心内科!山东泰安271000(李金龙,张艳玲)
摘    要:目的 观察疏甲丙脯酸对左室肥厚的消退作用。方法 观察45例高血压患者口服疏甲丙脯酸一年前后血压,左室形态结构变化,并与45例尼群地平组对比。结果 疏甲丙脯酸和尼群地平组治疗后左室重量指数(LVMI)均降低P〈0.001,两组疗效相似。提示两药能有效降低血压,逆转左室肥厚。结论 巯甲丙脯酸在治疗高血压左室肥厚时,可考虑为首选药物之一。

关 键 词:高血压 左室肥厚 药物疗法 巯甲丙脯酸 尼群地平

Efficacy comparison retween captopril and nitrendipine in the treatment of left ventricular hypertrophy on patients with hypertension
DOU Xue rong ,LI Jin long ,ZHANG Yan ling ,MENG Qing hua. Efficacy comparison retween captopril and nitrendipine in the treatment of left ventricular hypertrophy on patients with hypertension[J]. Journal of Taishan Medical College, 2000, 21(1): 32-33
Authors:DOU Xue rong   LI Jin long   ZHANG Yan ling   MENG Qing hua
Affiliation:DOU Xue rong 1,LI Jin long 2,ZHANG Yan ling 2,MENG Qing hua 1
Abstract:Objective: To observe the curative efficacy of captopril on left ventricular hypertrophy. Methods: The blood pressure and left ventricular structural changes of 45 patients with hypertrophy were studided before and after 1 year's treatment of captopril , and compared with those of 45 patients with nitrendipine treatment. Results: In treatment group and comparison group,LVMI both decreased to P<0.001,these two drugs had the same effect. Both could decrease blood pressure effectively and prevented left ventriculer hypertrophy. Conclusion: For the treatment of left ventricular hypertrophy in patients with hypertension, captopril could be selected as choice drugs.
Keywords:captopril  nitrendipine  primary hypertension  left ventricular hypertrophy
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