| 超声造影时间-强度曲线诊断前列腺癌 |
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| 引用本文： | 陆殿元,沈理,蔡建荣,陈玉华,陈亚青. 超声造影时间-强度曲线诊断前列腺癌[J]. 中国医学影像技术, 2015, 31(8): 1255-1258 |
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| 作者姓名： | 陆殿元 沈理 蔡建荣 陈玉华 陈亚青 |
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| 作者单位： | 上海交通大学医学院附属新华医院超声科, 上海 200092;,上海交通大学医学院附属新华医院崇明分院超声科, 上海 202150,上海交通大学医学院附属新华医院崇明分院超声科, 上海 202150,上海交通大学医学院附属新华医院崇明分院超声科, 上海 202150,上海交通大学医学院附属新华医院超声科, 上海 200092; |
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| 基金项目： | 国家自然科学基金面上项目(81271595)、上海市科学技术委员会科研计划项目(14140901802、10JC1411400、10411952000、09411963800)。 |
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| 摘 要： | 目的 探讨CEUS时间-强度曲线诊断前列腺癌的价值。方法 对117例可疑前列腺癌患者行经直肠CEUS检查,以穿刺病理证实前列腺癌和非前列腺癌病灶的部位作为定量分析的ROI,得到各部位的时间-强度曲线及达峰时间、增强强度、曲线下面积定量参数,分析病灶CEUS定量参数的差异。结果 前列腺癌86例(86/117,73.50%)、非前列腺癌31例(31/117,26.50%)。前列腺癌病灶的达峰时间早于非前列腺癌病灶,增强强度和曲线下面积均高于非前列腺癌病灶(P均<0.05);前列腺癌周缘区达峰时间早于非前列腺癌病灶周缘区,增强强度和曲线下面积高于非前列腺癌病灶周缘区(P均<0.01)。结论 CEUS时间-强度曲线有助于前列腺癌尤其是周缘区前列腺癌的鉴别诊断,可提高前列腺癌穿刺活检的阳性率。
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| 关 键 词： | 超声检查 前列腺肿瘤 造影剂 时间-强度曲线 定量分析 |
| 收稿时间： | 2015-03-11 |
| 修稿时间： | 2015-04-01 |
Time-intensity curve of contrast-enhanced transrectal ultrasonography in diagnosis of prostate cancer |
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| LU Dian-yuan,SHEN Li,CAI Jian-rong,CHEN Yu-hua and CHEN Ya-qing. Time-intensity curve of contrast-enhanced transrectal ultrasonography in diagnosis of prostate cancer[J]. Chinese Journal of Medical Imaging Technology, 2015, 31(8): 1255-1258 |
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| Authors: | LU Dian-yuan SHEN Li CAI Jian-rong CHEN Yu-hua CHEN Ya-qing |
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| Affiliation: | Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China;,Department of Ultrasound, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Chongming Branch, Shanghai 202150, China,Department of Ultrasound, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Chongming Branch, Shanghai 202150, China,Department of Ultrasound, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Chongming Branch, Shanghai 202150, China and Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China; |
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| Abstract: | Objective To investigate the clinical value of time-intensity curve of contrast-enhanced transrectal ultrasonography (CETRUS) in diagnosis of prostate cancer. Methods Totally 117 patients suspected of prostate cancer underwent CETRUS. Biopsy-proved prostate cancer lesions and non-prostate cancer lesions were selected as ROI, and time-intensity curve were reconstructed. The hemodynamic parameters including time-to-peak (TTP), peak intensity (PI) and area under the curve (AUC) were obtained. The differences of the hemodynamic parameters between prostate cancer and non-prostate cancer were analyzed. Results In all 117 patients, 86 (86/117, 73.50%) was prostate cancer and 31 (31/117, 26.50%) were non-prostate cancer. Compared with non-prostate cancer lesions, prostate cancer lesions had lower TTP, higher PI and AUC (all P<0.05). After dividing the lesions into peripheral zone (PZ) and transitional zone (TZ), statistical analysis revealed that the PZ prostate cancer lesions had lower TTP, higher PI and AUC than the non-prostate cancer lesions located in PZ (all P <0.01). Conclusion The quantitative analysis of CETRUS is helpful in the differential diagnosis of prostate cancer, especially the PZ prostate cancer, which can increase the positive rate of prostate biopsy. |
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| Keywords: | Ultrasonography Prostatic neoplasms Contrast media Time-intensity curve Quantitative analysis |
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