三维斑点追踪成像评价2型糖尿病患者左心室应变

目的 应用三维斑点追踪技术评价2型糖尿病(DM)患者左心室应变。方法 对30例2型DM患者(DM组)及30名健康志愿者(对照组)行三维斑点追踪成像,比较两组左心室整体及各节段应变。结果 DM组左心室收缩期整体应变(GS)、整体环向应变(GCS)、整体径向应变(GRS)及整体纵向应变(GLS)均低于对照组(t=2.18、3.27、2.05、3.76,P均<0.05)。DM组左心室前壁及侧壁环向收缩期峰值应变均低于对照组(P均<0.05);前壁基底段、中间段及侧壁径向收缩期峰值应变均低于对照组(P均<0.05);前间隔基底段、前壁基底段和中间段、侧壁中间段和心尖段、下壁心尖段纵向收缩期峰值应变均低于对照组(P均<0.05)。DM组基底段径向及纵向收缩期峰值应变均低于心尖段,中间段纵向收缩期峰值应变低于心尖段(P均<0.05)。对照组基底段环向、径向及纵向收缩期峰值应变均低于心尖段,中间段纵向收缩期峰值应变低于心尖段(P均<0.05)。结论 三维斑点追踪技术可用以评价2型DM左心室整体及节段收缩功能的早期改变。

Evaluation of left ventricular strain in patients with type-2 diabetes mellitus using three-dimensional speckle tracking

Objective To evaluate left ventricular strain in patients with type-2 diabetes mellitus (2-DM) using three-dimensional speckle tracking imaging (3D-STI). Methods Thirty patients with 2-DM (DM group) and 30 healthy volunteers (control group) underwent 3D-STI. The globe and segments of strain left ventricular were compared between groups. Results The global strain (GS), global circumferential strain (GCS), global radial strain (GRS), global longitudinal strain (GLS) in DM group were decreased than thoses in control group (t=2.18, 3.27, 2.05, 3.76, all P<0.05). The systolic peak circumferential strains of left ventricular anterior and lateral walls in 2-DM group were decreased than those in control group (both P<0.05). The systolic peak radial strains of lateral wall, basal and middle anterior walls in 2-DM group were decreased than those in control group (all P<0.05). The systolic peak longitudinal strains of basal anterior septum, basal and middle anterior walls, middle and apical lateral walls, apical inferior wall in 2-DM group were decreased than those in control group (all P<0.05). In DM group, the systolic peak radial and longitudinal strains of basal segment were decreased than those of apical segment, and the longitudinal strain of middle segment was decreased than that of apical segment (all P<0.05). In control group, the systolic peak circumferential, radial and longitudinal strains of basal segment were decreased than those of apical segment, and the longitudinal strain of middle segment were decreased than that of apical segment (all P<0.05). Conclusion 3D-ST is a useful technology not only in evaluating global function of left ventricular, but also in detecting early changes in segments.