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二维超声、实时组织弹性成像及声触诊组织量化技术诊断乳腺浸润性导管癌
引用本文:李军,袁美芹,成静,杜婷婷,王甲嘉,芦桂林. 二维超声、实时组织弹性成像及声触诊组织量化技术诊断乳腺浸润性导管癌[J]. 中国医学影像技术, 2015, 31(8): 1234-1237
作者姓名:李军  袁美芹  成静  杜婷婷  王甲嘉  芦桂林
作者单位:石河子大学医学院第一附属医院功能科, 新疆 石河子 832000,石河子大学医学院第一附属医院功能科, 新疆 石河子 832000,石河子大学医学院第一附属医院功能科, 新疆 石河子 832000,石河子大学医学院第一附属医院功能科, 新疆 石河子 832000,石河子大学医学院第一附属医院功能科, 新疆 石河子 832000,石河子大学医学院第一附属医院功能科, 新疆 石河子 832000
摘    要: 目的 探讨二维超声(2D-US)、实时组织弹性成像(UE)及声触诊组织量化(VTQ)技术对乳腺浸润性导管癌(IDC)的诊断价值。方法 对188例患者共213个乳腺病灶术前分别行2D-US、UE及VTQ检查,对各病灶2D-US声像图表现进行超声乳腺影像报告数据系统(BI-RADS-US)分类,UE采用5级评分法判断结节性质,VTQ技术定量测定结节内剪切波速度(SWV)。绘制ROC曲线,比较2D-US、UE、SWV曲线下面积(AUC)。结果 2D-US诊断IDC的敏感度为82.35%(126/153),特异度为71.67%(43/60),准确率为79.34%(169/213)。UE诊断IDC的敏感度为86.27%(132/153),特异度为73.33%(44/60),准确率为82.63%(176/213)。良性及恶性结节的SWV别为(3.09±1.26)m/s、(6.83±2.18)m/s(P<0.05);以3.59 m/s作为诊断恶性病灶的最佳截断值,VTQ诊断IDC的敏感度为86.93%(133/153),特异度为76.67%(46/60),准确率为84.04%(179/213)。2D-US、UE、SWV诊断乳腺IDC的AUC分别为0.811、0.843、0.899,差异有统计学意义(P<0.01)。结论 US、UE及VTQ均有助于鉴别诊断乳腺良性结节及乳腺IDC,UE优于2D-US,VTQ可获得客观的量化指标,重复性好,优于UE和2D-US。

关 键 词:乳腺肿瘤  弹性成像技术  声触诊组织量化  超声检查
收稿时间:2014-11-27
修稿时间:2015-05-02

Two-dimensional ultrasound, real-time tissue ultrasonic elastography and virtual touch tissue quantification in diagnosing breast infiltrative ductal carcinoma
LI Jun,YUAN Mei-qin,CHENG Jing,DU Ting-ting,WANG Jia-jia and LU Gui-lin. Two-dimensional ultrasound, real-time tissue ultrasonic elastography and virtual touch tissue quantification in diagnosing breast infiltrative ductal carcinoma[J]. Chinese Journal of Medical Imaging Technology, 2015, 31(8): 1234-1237
Authors:LI Jun  YUAN Mei-qin  CHENG Jing  DU Ting-ting  WANG Jia-jia  LU Gui-lin
Affiliation:Department of Ultrasound Function Branch, the First Affiliated Hospital of Shihezi University, Shihezi 832000, China,Department of Ultrasound Function Branch, the First Affiliated Hospital of Shihezi University, Shihezi 832000, China,Department of Ultrasound Function Branch, the First Affiliated Hospital of Shihezi University, Shihezi 832000, China,Department of Ultrasound Function Branch, the First Affiliated Hospital of Shihezi University, Shihezi 832000, China,Department of Ultrasound Function Branch, the First Affiliated Hospital of Shihezi University, Shihezi 832000, China and Department of Ultrasound Function Branch, the First Affiliated Hospital of Shihezi University, Shihezi 832000, China
Abstract:Objective To investigate the value of two-dimensional ultrasound (2D-US), ultrasonic elastography (UE) and virtual touch tissue quantification (VTQ) in diagnosing breast infiltrative ductal carcinoma (IDC). Methods 2D-US, UE and VTQ were used to examine 188 patients with 213 breast lesions before operation, 2D-US images was classified with breast image reporting and data system-ultrasound, 5-score evaluation was performed in UE, and shear wave velocity (SWV) was determined with VTQ. ROC curve was drown, of area under curve (AUC) of 2D-US, UE and SWV was compared. Results The sensibility, specificity, accuracy of 2D-US for diagnosing IDC was 82.35% (126/153), 71.67% (43/60), 79.34% (169/213), of UE was 86.27% (132/153), 73.33% (44/60), 82.63% (176/213). The SWV of benign lesions and IDC were (3.09±1.26)m/s and (6.83±2.18)m/s (P<0.05). The sensibility, specificity, accuracy was 86.93% (133/153), 76.67% (46/60), 84.04% (179/213) when SWV was 3.59 m/s as cut-off value. AUC of 2D-US, UE, SWV was 0.811, 0.843, 0.899 (P<0.01). Conclusion US, UE and VTQ are helpful in differentiating IDC and benign breast nodules, and UE is better than 2D-US, while VTQ can get objective quantification index and be easy to be repeated, and is superior to UE and 2D-US.
Keywords:Breast neoplasms  Elastic imaging technology  Virtual touch tissue quantification  Ultrasonography
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