喷他佐辛联合氟比洛芬在腹腔镜妇科手术术后多模式镇痛的临床应用

目的 探讨喷他佐辛联合氟比洛芬在腹腔镜妇科术术后多模式镇痛的临床应用效果。方法 本院A S AⅠ‐Ⅱ级行择期腹腔镜妇科手术的患者70例，随机分为试验组和对照组，试验组：术后喷他佐辛加氟比洛芬持续静脉镇痛；对照组：术后仅采用喷他佐辛持续静脉镇痛。采取视觉模拟评分法（VAS）、布氏舒适度（BCS）评分评定镇痛效果，统计比较两组术后不良反应发生率、术后喷他佐辛用量、自控静脉镇痛（PCA ）综合满意度评分。结果 术后6～48 h ，两组患者VAS评分分值均随时间推迟逐渐降低，BCS评分分值随时间推迟逐渐升高，与对照组比较，试验组各时点分值均显著降低或增高（ P ＜0．05）；试验组在术后8、12、l6、20、24 h时间段喷他佐辛阶段性用量及术后0～12、0～24、0～36、0～48 h内喷他佐辛阶段性使用总量均明显少于对照组（ P ＜0．05）。试验组和对照组不良反应发生率无显著差别，试验组PCA满意度评分显著高于对照组（ P ＜0．05）。结论 腹腔镜妇科手术术后喷他佐辛联合氟比洛芬多模式镇痛明显优于术后单纯喷他佐辛镇痛。多模式镇痛能够提高术后镇痛效果，减少术后喷他佐辛的用量，提高其住院满意度。

Clinical Application of Pentazocine Combined with Flurbiprofen in Multimodal Analgesia after Laparoscopic Gynecologic Surgery

Objective] To explore clinical application efficacy of pentazocine combined with flurbiprofen in multimodal analgesia after laparoscopic gynecologic surgery .[Methods]A total of 70 ASA Ⅰ ~ Ⅱ patients under‐going laparoscopic gynecologic surgery were randomly divided experimental group and control group .The experi‐mental group received intravenous continuous analgesia with pentazocine and flurbiprofen postoperatively . The control group only received intravenous continuous analgesia with pentazocine postoperatively .Visual analogue scale（VAS） score and Bruggrmann comfort scale（BCS） were used to assess the analgesia effect .The incidence of postoperative adverse reaction ,postoperative dose of pentazocine ,patients controlled analgesia（PCA） and compre‐hensive satisfaction score in two groups were compared .[Results]At 6~48h after operation ,VAS scores in two groups were gradually reduced with the time delay ,while BCS scores were gradually increased with the time delay . Compared with the control group ,the scores in the experimental group at each time point were markedly decreased or increased（ P 〈0 .05） .The stage dose of pentazocine at 8h ,12h ,l6h ,20h and 24h and the total amount of pen‐tazocine at 0~12 ,0~24 ,0~36 and 0~48h in experimental group were less than those in control group（ P 〈0 .05） .There was no significant difference in the incidence of adverse reaction between experimental group and control group .PCA satisfaction scores in experimental group were markedly higher than those in control group（ P〈0 .05） .[Conclusion]Pentazocine combined with flurbiprofen for multimodal analgesia after laparoscopic gyneco‐logic surgery is better than simple pentazocine .Multimodal analgesia can improve postoperative analgesia effect , reduce pentazocine consumption and increase hospitalization satisfaction of patients .