依达那奉治疗急性脑梗死32例临床观察

目的 探讨依达那奉治疗急性脑梗死的临床疗效。方法 随机选择2012年1月至2013年12月本院收治的64例急性脑梗死患者,所有患者均在发病24 h内到医院诊治。随机将这些患者分为试验组和对照组,每组各32例。对照组常规给予血塞通针静脉滴注;试验组在对照组的基础上给予依达那奉治疗,观察两组的治疗结果。结果 试验组有31例患者治疗有效,1例为无效,有效率为96．9％（31／32）;对照组30例患者治疗有效,2例无效,有效率为93．8％（30／32）。两组的总有效率比较差异无统计学意义;两组治疗后NIHSS评分和Bathel指数均较治疗前有明显的改善（均 P ＜0．05）,且试验组明显优于对照组差异有统计学意义（均 P ＜0．05）。结论 在脑梗死早期使用依达那奉治疗,改善神经功能缺损症状,值得临床推广应用。

Clinical Observation of Edaravone for the Treatment of Cerebral Infarction

Objective] To explore clinical efficacy of edaravone for the treatment of cerebral infarction .[Methods] A total of 64 patients with cerebral infarction in our hospital form Jan .2012 to Dec .2013 were randomly selected .All patients were admitted to the hospital for the diagnosis and treatment within 24h of on‐set .These patients were randomly divided into experimental group（ n=32） and control group（ n =32） .The control group was given intravenous instillation with conventional Xuesaitong needle ,while the experimental group was given edaravone based on the treatment of control group .The treatment results of two groups were observed .[Results] In experimental group ,31 patients were effective treatment ,and 1 patient was invalid , and the effective rate was 96 .9% （31/32） .In control group ,30 patients were effective treatment ,and 2 pa‐tients were invalid ,and the effective rate was 93 .8% （30/32） .There is no significant difference in the total ef‐fective rate between two groups .Compared with before treatment ,NIHSS score and Bathel index of two groups after treatment were obviously improved（all P〈0 .05） ,and those in experimental group were obvious‐ly better than the control group ,and there was significant difference（all P〈0 .05） .[Conclusion]Edaravone for early treatment of cerebral infarction can improve the symptoms of neurologic impairment .Therefore ,it is worthy of clinical promotion .