阿司匹林维生素C分散片治疗急性上呼吸道感染的随机对照临床研究

目的评价阿司匹林维生素C分散片治疗上呼吸道感染的临床疗效和安全性。方法确诊的急性上呼吸道感染患者45例,其中治疗组23例,口服阿司匹林维生素C分散片,1片,3次/d;对照组22例,口服拜阿司匹灵维C泡腾片,1片,3次/d;疗程均为2～3d。结果单次用药后,治疗组和对照组解热的有效率分别为78.3%(18/23)和77.3%(17/22)(P=1.0)。综合疗效分析,治疗组和对照组有效率分别为82.6%(19/23)和94.5%(21/22)。两组比较无统计学差异(P>0.05)。两组不良反应发生率均较低且无统计学差异(4.4%VS0%,P>0.05)。结论阿司匹林维生素C分散片能安全有效地治疗急性上呼吸道感染。

A Randomly Controlled Clinical Trial of Aspirin-vitamin C Dispersible Tablets in Patients with Acute Upper Respiratory Tract Infection

Objective To evaluate the efficacy and safety of Aspirin-vitamin C dispersible tablets in treating upper respiratory tract infection (URI). WTHZ]Methods Forty-five patients with URI were included in the present trial. Twenty-three patients were treated with Aspirin-vitamin C dispersible tablets, and the other matched twenty-two patients were treated with Bayaspirin-vitamin C effervescent tablets. Results The efficient rate in the two groups receiving the first single dose of Aspirin-vitamin C or Bayaspirin-vitamin C was 78.3% and 77.3%, respectively (P=1.0). There was no statistical difference in overall efficient rate between the two groups (82.6% vs 94.5%, P>0.05). The incidence of side effect in the two groups was low, and had not significant difference between the two groups (4.4% vs 0%,P>0.05). Conclusion Aspirin-vitamin C dispersible tablets is effective and safe for treating patients with URI.