| 羊红膻根中羊红膻素A及羊红膻素B的分离和鉴定 |
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| 引用本文： | 乔博灵,王长岱,米彩峰,李富贤,石慧丽,高岛纯子.羊红膻根中羊红膻素A及羊红膻素B的分离和鉴定[J].药学学报,1997,32(1):56-58. |
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| 作者姓名： | 乔博灵 王长岱 米彩峰 李富贤 石慧丽 高岛纯子 |
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| 作者单位： | 陕西省中医药研究院中药研究所，日本三菱化成综合研究所 |
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| 摘 要： | 从草药羊红膻(Pimpinela thelungiana Wolf)根中分得2个化合物,经光谱解析(UV,IR,MS,1HNMR,1H 1HCOSY,13CNMR,13C-1HCOSY和DEPT),鉴定为2-(1-ethoxy-2-hydroxy)propyl-4-methoxyphenol(I)和2-(1-ethoxy-2-hydroxy)propyl-4-methoxyphenyl-2-methyl-butyrate(II),分别命名为羊红膻素A及羊红膻素B,为2个新的天然产物,药理实验表明这2个新化合物均有较明显的降压活性。
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| 关 键 词： | 羊红膻根 2-(1-乙氧基-2-羟基)丙基-4-甲氧基苯酚 2-(1-乙氧基-2-羟基)丙基-4-甲氧基苯酚-2-甲基丁酸酯 |
| 收稿时间： | 1996-01-06 |
SEPARATION AND IDENTIFICATION OF THE LLUNGIANIN A AND B FROM THE ROOT OF PIMPINELLA THELLUNGIANA WOLFF |
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| BL Qiao,CD Wang,CF Mi,FX Li,HL Shi and J Takashima.SEPARATION AND IDENTIFICATION OF THE LLUNGIANIN A AND B FROM THE ROOT OF PIMPINELLA THELLUNGIANA WOLFF[J].Acta Pharmaceutica Sinica,1997,32(1):56-58. |
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| Authors: | BL Qiao CD Wang CF Mi FX Li HL Shi and J Takashima |
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| Institution: | Shaanxi Provincial Academy of Traditional Chinese Medicine and Materia Medica, Academy of Traditional Chinese Materia Medica, Xian 710003. |
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| Abstract: | Two compounds were isolated from the roots of Pimpinella thellungiana wolff. On the basis of spectral analysis (UV,IR,MS, 1HNMR, 1H 1H COSY, 13 CNMR, 1H 13 C COSY,DEPT), they were identified as 2 (1 ethoxy 2 hydroxy) propyl 4 methoxyphenol(I); 2 (1 ethoxy 2 hydroxy) propyl 4 methoxyphenyl 2 methyl butyrate(II). They are new compounds named the llungianin A and B. Pharmacological tests showed that they have some hypotensive effects. |
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| Keywords: | Pimpinella thellungiana Wolff 2 (1 Ethoxy 2 hydroxy) propyl 4 methoxyphenol 2 (1 Ethoxy 2 hydroxy) propyl 4 methoxyphenyl 2 methyl butyrate |
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