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地佐辛联用舒芬太尼对妇科术后镇痛效果的临床观察
引用本文:张帆,章杭,李丰. 地佐辛联用舒芬太尼对妇科术后镇痛效果的临床观察[J]. 中国临床药理学与治疗学, 2012, 17(3): 342-345
作者姓名:张帆  章杭  李丰
作者单位:杭州市肿瘤医院麻醉科,杭州310002,浙江
摘    要:目的:观察地佐辛联用舒芬太尼对妇科术后静脉镇痛的临床效果。方法:按照入院顺序将150例妇科术后患者,随机分为地佐辛组、舒芬太尼组、地佐辛联合舒芬太尼组。静脉镇痛记录术后24、48h的视觉模拟评分(VAS)、舒适度评分(BCS)、镇静评分(Ramsay)、呕吐评分,记录各种不良反应情况。结果:地佐辛组、舒芬太尼组、地佐辛联合舒芬太尼组之间用药后24h和48h比较:联合用药组VAS、BCS、呕吐评分较佳,差异均具有统计学意义(P<0.05);不良反应除了木僵、呼吸频率和平均动脉压三者之间的差异不明显(P>0.05),其他指标联合组优于其他两组,且差异具有统计学意义(P<0.05)。结论:地佐辛联合舒芬太尼用于妇科术后静脉镇痛临床效果佳。

关 键 词:地佐辛  舒芬太尼  妇科  术后  静脉镇痛

Compare the clinical effects of obstetrics and gynecology intravenous injection for postoperative analgesia with Sufentanil and Dezocine
ZHANG Fan , ZHANG Hang , LI Feng. Compare the clinical effects of obstetrics and gynecology intravenous injection for postoperative analgesia with Sufentanil and Dezocine[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2012, 17(3): 342-345
Authors:ZHANG Fan    ZHANG Hang    LI Feng
Affiliation:Department of Anesthesiology,Wushan District,Hangzhou First People’s Hospital,Hangzhou 310002,Zhejiang,China
Abstract:AIM: To observe and analyse the clinical effects of gynecology intravenous injection for postoperative analgesia with Sufentanil and Dezocine.METHODS: 150 cases of obstetrics and gynecology patients were randomly divided into groups of Dezocine,Sufentanil,Dezocine joint Sufentanil.24,48 h after intravenous analgesia recorded the VAS,BCS,Ramsay score,vomiting score,recorded a variety of adverse reactions.RESULTS:Compared between 24 h and 48 h among Dezocine group,Sufentanil group and Sufentanil combined with Zuoxin Group,Sufentanil combined with Zuoxin Group had higher VAS,BCS,vomiting score,and there were statistically significant among three groups(P<0.05).Adverse reactions in addition to stupor,respiratory rate and mean arterial pressure had no significantly different between three groups(P>0.05),the jiont group had better results than those of other two groups in other indicators(P<0.05).CONCLUSION: Postoperative analgesia with Sufentanil combined with Dezocine for gynecology intravenous injection has good clinical effects.
Keywords:Dezocine  Sufentanil  Gynecology  Postoperative  Intravenous analgesia
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