| 偏痛胶囊流浸膏镇痛抗炎作用实验研究 |
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| 引用本文： | 徐暾海,文萍,刘斌,张小勇,贾萧荣,陶晓华.偏痛胶囊流浸膏镇痛抗炎作用实验研究[J].中国临床药理学与治疗学,2012,17(8):874-877. |
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| 作者姓名： | 徐暾海 文萍 刘斌 张小勇 贾萧荣 陶晓华 |
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| 作者单位： | 北京中医药大学,北京,100029 |
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| 基金项目： | 北京市教育委员会在京高校共建项目 |
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| 摘 要： | 目的:研究偏痛胶囊流浸膏镇痛、抗炎药效学作用.方法:热板法、醋酸扭体法观察偏痛胶囊流浸膏对小鼠的镇痛作用,二甲苯致小鼠耳肿胀、蛋清致大鼠足肿胀的方法研究偏痛胶囊流浸膏的抗炎作用.结果:偏痛胶囊流浸膏能明显减少醋酸致小鼠扭体次数,显著提高小鼠痛阈值(P＜0.01或P＜0.05)；明显抑制小鼠耳肿胀,减少耳重差,对大鼠足跖肿胀有显著抑制作用(P＜0.01或P＜0.05).结论:偏痛胶囊流浸膏具有较好的镇痛、抗炎作用.
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| 关 键 词： | 偏痛胶囊 流浸膏 镇痛 抗炎 |
Experimental study of PIANTONG capsule fluid extract on analgesic and anti-inflammatory effect |
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| XU Tun-hai
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WEN Ping
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LIU Bin
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ZHANG Xiao-yong
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JIA Su-rong
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TAO Xiao-hua.Experimental study of PIANTONG capsule fluid extract on analgesic and anti-inflammatory effect[J].Chinese Journal of Clinical Pharmacology and Therapeutics,2012,17(8):874-877. |
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| Authors: | XU Tun-hai WEN Ping LIU Bin ZHANG Xiao-yong JIA Su-rong TAO Xiao-hua |
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| Institution: | Beijing University of Chinese Medicine,Beijing 100029,China |
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| Abstract: | AIM:To investigate the analgesic,and anti-inflammatory effects of PIANTONG capsule fluid extract.METHODS: The analgesic action was detected through the hot-plate and acetic acid-induced writhing test in mice,regarding to pain threshold and stretching times.The anti-inflammation effect of PIANTONG capsule fluid extract was tested by xylene-induced mouse ear swelling and albumen-induced rat hind paw swelling.RESULTS:PIANTONY capsule fluid extract obviously decreased the writhing time,significantly prolonged the pain threshold of mice and inhibited ear swelling and hind paw swelling.CONCLUSION: PIANTONG capsule possesses significant anti-inflammatory and analgesic effects. |
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| Keywords: | PIANTONG capsule Fluid extract Relieve pain Anti-inflammation |
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