地佐辛复合氟比洛芬酯在脊柱后路手术术后镇痛中的效果

目的:观察地佐辛复合氟比洛芬酯用于脊柱后路手术术后静脉自控镇痛(patient con-trolled intravenous analgesia,PCIA)的效果。方法:60例行脊柱后路内固定手术的患者,随机均分为地佐辛复合氟比洛芬酯组(DF组)、舒芬太尼组(S组),每组30例。观察两组患者术后1、4、8、12、24、36、48h在安静时及翻身运动时视觉模拟评分(VAS)、镇静程度评分(Raesay)、48h内患者自控镇痛(patient controlled analgesia,PCA)有效按压次数与实际按压次数比、患者镇痛满意度、总体评价及不良反应的发生情况。结果:两组配方均能为患者提供良好的术后镇痛,有效按压次数与实际按压次数比两组相近(P>0.05);DF组患者在翻身运动时的VAS评分、镇痛满意度及总体评价显著优于S组(P<0.05),不良反应发生率低(P<0.05)。结论:地佐辛复合氟比洛芬酯用于脊柱后路手术PCIA,镇痛效果良好,不良反应发生率低。

Analgesic effects of dezocine combining with flurbiprofen after posterior spinal approach

AIM: To observe the analgesic effects of dezocine combining with flurbiprofen in patient controlled intravenous analgesia(PCIA) after posterior spinal approach.METHODS: Sixty patients undergoing posterior spinal internal fixation surgery were equally randomized into two groups : dezocine combining with flurbiprofen group(Group DF,n=30),and sufentanil group(Group S,n=30).Visual analogue scale(VAS) in the quiet time and movement in the stand,and Ramsay sedation scale were evaluated at 1,4,8,12,24,36 and 48 h after surgery;the number of effective compression ratio and the actual number of pressing within 48 h PCA,patient satisfaction with pain,overall assessment of pain patients and the incidence of adverse reactions were also recorded.RESULTS:The two groups were able to provide good postoperative analgesia,the number of effective compression ratio and the actual number of pressing were similar(P>0.05).DF group’s VAS scores movement in the stand,patient satisfaction with pain and overall assessment of pain patients were significantly better than those in the S group(P<0.05),and had lower incidence of adverse reactions(P<0.05).CONCLUSION: Dezocine combining with flurbiprofen can provide satisfactory postoperative analgesia after posterior spinal approach,and has lower incidence of adverse reactions.