FAILURE OF PNEUMOCOCCAL VACCINATION IN A SPLENECTOMIZED CHILD |
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| Authors: | J. LANNG NIELSEN F. KARUP PEDERSEN J. ELLEGAARD |
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| Affiliation: | University Department of Medicine and Haematology, Aarhus Amtssygehyus, Aarhus, and W. H. O. Collaborating Centre for Reference and Research on Pneumococci, Statens Seruminstitut, Copenhagen, Denmark |
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| Abstract: | ABSTRACT. Recurrent Streptococcus pneumoniae septicaemia occurred in a splenectomized child with idiopathic thrombocytopenic purpura. Fatal infection took place 1 year after pneumococcal vaccination and was caused by sero-type 18C which was included in the vaccine. The efficacy of pneumococcal vaccination is discussed in relation to specific pneumococcal polysaccharide antibody titers, and it is concluded that vaccination alone is insufflcient in preventing overwehlming infections in splenectomized Individuals. |
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| Keywords: | Failure of pneumococcal vaccination pneumococcal vaccine splenectomy Streptococcus pneumoniae bacteremia Streptoccus pneumoniae meningitis |
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