口服枸橼酸铁铵在胆胰系MRI中的应用价值评价

目的:评价口服枸橼酸铁铵在胆胰系MRI中的应用价值。方法:对86例怀疑有胰胆管系统疾病的患者行口服枸橼酸铁铵前、后MRCP及常规胆胰系MRI,对服用对比剂前后MRCP图像质量、邻近脏器边缘分辨力及各序列上胃十二指肠腔与肝脏的对比噪声比进行自身对照研究,由资深放射科医生对两组图像进行评价,SPSS统计软件进行统计分析。结果:服用对比剂后TrueFISP及HASTE序列均显示胃、十二指肠腔内信号显著降低,形成阴性对比;而FL2D序列胃、十二指肠腔内信号增强,形成阳性对比;胃十二指肠腔内液体造成的背景高信号被完全抑制,单层法与多层法MRCP图像质量及邻近的肝胆胰等结构边缘分辨力均明显提高。结论:口服枸橼酸铁铵能明显提高胆胰系MRI的成像质量,对诊断胆胰系病变具有重要的临床应用价值。

Oral Administration of Ferric Ammonium Citrate Solution as a Gastrointestinal Contrast Agent for Magnetic Resonance Imaging of Biliary Tract and Pancreas

Objective:To evaluate the value of oral administration of ferric ammonium citrate solution as a gastrointestinal contrast agent for magnetic resonance imaging of biliary tract and pancreas.Methods:Oral administration of ferric ammonium citrate solution before and after MRCP and conventional MRI were performed in 86 patients which were suspected of having biliary tract and pancreatic disease.Comparison of the image quality of MRCP,resolution of differentiating the anatomic configuration of adjacent visceral organs,the contrast -noise ratio of varied sequences between lumen of gastrointestinal tract and liver before and after oral contrast administration were studied by two senior radiologists.SPSS software package was used for statistical analysis.Results:The signal intensity of the gastrointestinal tract reduced remarkably on True FISP (true fast imaging with steady state precession) sequence and HASTE (half Fourior acquisition single shot turbo spin echo) sequence,while enhanced on FL2D (two dimensional fast low angle shot) sequence after contrast administration,the adjacent structures were well delineated.The hyperintense fluid within the lumen of stomach and duodenum was completely suppressed,making the image quality of single-slice and multi-slice MRCP significantly improved.Conclusion:Oral administration of ferric ammonium citrate solution administration can significantly improve the image quality of magnetic resonance imaging of biliary tract and pancreas,it plays an essential role in the clinical diagnosis of their diseases.