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| 陶瓷正畸托槽材料的生物安全性初步评价 | |
| 引用本文： | 肖立民,吴恩格,税艳青,陈亚娟. 陶瓷正畸托槽材料的生物安全性初步评价[J]. 口腔材料器械杂志, 2005, 14(1): 18-20 |
| 作者姓名： | 肖立民 吴恩格 税艳青 陈亚娟 |
| 作者单位： | 1. 昆明医学院口腔学院,昆明,650031 2. 昆明医学院附属第一医院 3. 昆明医学院天然药物实验室 |
| 摘 要： | 目的采用细胞毒性试验、口腔黏膜刺激实验对一种陶瓷正畸托槽材料的生物安全性进行初步的评价.方法根据国家标准,应用体外细胞培养琼脂覆盖法对这种陶瓷材料进行细胞毒性评价,利用大耳白兔检测这种陶瓷材料对口腔黏膜的刺激反应.结果这种陶瓷材料的细胞毒性试验评级为0级,口腔黏膜刺激试验中试验动物未见局部及全身的不良刺激反应(包括组织学观察).结论这种陶瓷材料不具有细胞毒性及对口腔黏膜的不良刺激反应. |
| 关 键 词： | 陶瓷 正畸托槽 细胞毒性 口腔黏膜刺激试验 |
| 修稿时间： | 2004-09-24 |
Preliminary evaluation of biocompatibility on a ceramic of orthodontic bracket |
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| Xiao Limin,Wu Enge,Shui Yanqing,Chen Yajuan. Preliminary evaluation of biocompatibility on a ceramic of orthodontic bracket[J]. Chinese Journal of Dental Materials and Devices, 2005, 14(1): 18-20 | |
| Authors: | Xiao Limin Wu Enge Shui Yanqing Chen Yajuan |
| Abstract: | Objective The aim of this study was to evaluate the biocompatibility of a ceramic of orthodontic bracket by cytotoxicity and oral mucous membrane irritation test. Methods According to the relative Chinese national standards, the cytotoxicity of this ceramic was investigated by cell culture in vitro and agar diffusion test, and the oral mucous membrane irritation response of this ceramic was evaluated using rabbits. Results The results showed the level of cytotoxicity of this ceramic was grade 0, and the local or systemic abnormal response on rabbits including histopathological findings was not observed in the oral mucous membrane irritation test. Conclusion This ceramic has no cytotoxicity or abnormal oral mucous membrane irritating response. |
| Keywords: | Ceramic Orthodontic bracket Cytotoxicity Oral mucous membrane irritation test |
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