| 银杏叶提取物泡腾片的研制及质量考察 |
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| 引用本文： | 胡林水,郑珺,邵胜荣.银杏叶提取物泡腾片的研制及质量考察[J].中药材,2005,28(1):52-54. |
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| 作者姓名： | 胡林水 郑珺 邵胜荣 |
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| 作者单位： | 浙江康恩贝制药股份有限公司,浙江金华,321100 |
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| 摘 要： | 目的:研制银杏叶提取物泡腾片并建立该制剂的质量控制标准.方法:以pH值、崩解时限、第30日的硬度为评价指标,采用正交试验进行工艺优化,并对产品的稳定性进行了考察.结果:最佳工艺配比为枸橼酸12.5%,碳酸氢钠20%,采用聚乙二醇6000包裹碳酸氢钠,其产品经稳定性考察表明,本产品质量稳定.结论:本工艺可作为银杏叶提取物新剂型的开发.
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| 关 键 词： | 银杏叶提取物 泡腾片 正交设计 质量考察 |
| 修稿时间： | 2004年7月21日 |
Study on the Preparation of Effervescent Tablets of EGb and Its Quality |
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| Hu Linshui,Zheng Jun,Shao Shengrong.Study on the Preparation of Effervescent Tablets of EGb and Its Quality[J].Jorunal of Chinese Medicinal Materials,2005,28(1):52-54. |
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| Authors: | Hu Linshui Zheng Jun Shao Shengrong |
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| Institution: | Zhejiang CONBA Pharmaceutical Co. Ltd, Zhejiang, Lanxi 321100. |
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| Abstract: | Objective: To prepare effervescent tablets of EGb and establish quality preparation Method: Taking pH, disintegration time and rigidity as index, the formulation and technique of EGb effervescent tablets were optimized by orthogonal experiment, the products were prepared and its stability were tested Result: The optimum procedure condition was adding 12 5% citric acid, 20% sodium bicarbonate encapsulated by PEG6000, the products were tested by stability, the preparation was stable Conclusion: It is valuable to be further studied as a new preparation of EGb |
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| Keywords: | Extract of Ginkgo biloba (EGb) Effervescent Tablet Orthogonal experiment Quality control |
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