| DNA生物传感器在“基因诊断”中的实验研究 |
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| 引用本文： | 刘芳,刘仲明,李家洲. DNA生物传感器在“基因诊断”中的实验研究[J]. 中国医疗器械杂志, 2004, 28(1): 37-39 |
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| 作者姓名： | 刘芳 刘仲明 李家洲 |
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| 作者单位： | 广州军区广州总医院医学实验科,广东,广州,510010 |
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| 基金项目： | 广东省科技攻关项目，广东省广州市科技攻关项目 |
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| 摘 要： | 为了建立石英晶体DNA传感器检测乙肝病毒基因的方法,在石英晶体金表面固定单链DNA,构成压电晶体HBV DNA生物传感器,与待测样品进行杂交反应.结果DNA传感器能准确的诊断血清中的HBV病毒基因.石英晶体HBV DNA生物传感器具有操作省时、简单,能用于临床实验、诊断、检测.
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| 关 键 词： | DNA生物传感器 石英晶体:诊断 |
| 文章编号： | 1671-7104(2004)01-0037-03 |
| 修稿时间： | 2002-03-18 |
The Research of DNA Biosensor for Gene Diagnoses |
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| LIU Fang. LIU Zhong-ming,Ll Jia-zhou. The Research of DNA Biosensor for Gene Diagnoses[J]. Chinese journal of medical instrumentation, 2004, 28(1): 37-39 |
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| Authors: | LIU Fang. LIU Zhong-ming Ll Jia-zhou |
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| Affiliation: | LIU Fang. LIU Zhong-ming,Ll Jia-zhou.Department of Medical Experiment,General Hospital of GuangZhou Command |
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| Abstract: | In order to construct a new type of piezoelectric quartz crystal DNA biosensor for HBV, the single-chain DNA sequence is immobilized on the surface of gilt quartz crystal to make a HBV gene sensor, then to hybridize on the gene sensor in the serum sample. The quartz crystal DNA biosensor is able to detect the HBV exactly in the real HBV serum sample. The piezoelectric quartz crystal DNA biosensor is a fast dignostic tool with easy operation for detecting HBV in clinical laboratories. |
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| Keywords: | DNA biosensor quartz crystal diagnosis |
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