Prognostic indicators estimated by Tc-GSA in acute liver damage |
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| Authors: | Takashi Monoe Haruhisa Nakao Satoshi Sobue Yaichi Mizuno Syunsuke Nojiri Takayoshi Kanematsu Katsuhiro Senda Hitoshi Ohmi Hirotaka Ohara Takashi Joh Kazuyuki Itoh |
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| Institution: | a Kasugai City Hospital Internal Medicine, Japan
b Department of Internal Medicine and Bioregulation, Nagoya University Graduate School of Medical Sciences, 1 Kawasumi Mizuho-cho Mizuho-ku, Nagoya city 467-8601, Japan |
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| Abstract: | A prognostic estimation formula of acute liver damage was evaluated by using clinical data and technetium-99m-diethylenetriaminepentaacetic acid-galactosyl-human serum albumin (99mTc-GSA) scintigraphy in order to determine operability for orthotopic liver transplantation (OLT). Forty-six patients hospitalized for acute liver damage were divided into survival (n = 35) and non-survival (n = 11) groups. Univariate and multivariate analyses were used to identify significant factors that affected prognosis. Logistic regression analysis was performed to predict prognosis with effective factors. Ten independent factors with significant differences were identified and further analyzed for significance by logistic regression analysis. Among the 10 factors, age and LHL15/HH15 were identified as having meaningful differences for predicting convalescence. The following formula was developed: |
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| Keywords: | 99mTc-GSA Prognosis Acute liver damage |
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