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| 基于物质基础组分的中药多元释药 系统研究思路与应用 | |
| 引用本文： | 孙娥,贾晓斌,黄洋,陈斌,胡琴,萧伟. 基于物质基础组分的中药多元释药 系统研究思路与应用[J]. 中国中药杂志, 2012, 37(14): 2181-2185 |
| 作者姓名： | 孙娥 贾晓斌 黄洋 陈斌 胡琴 萧伟 |
| 作者单位： | 1. 江苏省中医药研究院 国家中医药管理局中药释药系统重点研究室,江苏南京,210028 2. 江苏省中医药研究院 国家中医药管理局中药释药系统重点研究室,江苏南京210028;中药制药过程新技术国家重点实验室(筹),江苏连云港222001 3. 江苏省中医药研究院 国家中医药管理局中药释药系统重点研究室,江苏南京210028;江苏大学药学院,江苏镇江212013 4. 中药制药过程新技术国家重点实验室(筹),江苏连云港,222001 |
| 基金项目： | 江苏省中医药领军人才项目(2006);中药制药过程新技术国家重点实验室开放基金项目(SKL2010Z0303);江苏省中医药科技项目(LZ09061,LZ09067) |
| 摘 要： | 该文针对中药制剂的研究现状,以"整体观念"和"辨证论治"为指导,依据中药多组分、多靶点、多效应的特点,提出"基于物质基础组分的中药多元释药系统"研究思路,建立"以物质基础组分为前提,以提高生物利用度为目的,构建中药多元释药系统"的中药制剂研究新模式,并以通脉微丸多元释药系统为例进行阐述,为中药现代给药系统的深入发展提供新的策略和方法。 |
| 关 键 词： | 中药多元释药系统 物质基础组分 生物利用度 通脉微丸 |
| 收稿时间： | 2011-12-06 |
Thought and application of traditional Chinese medicine multiple drug delivery system based on material basis component |
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| SUN E,JIA Xiaobin,HUANG Yang,CHEN Bin,HU Qin and XIAO Wei. Thought and application of traditional Chinese medicine multiple drug delivery system based on material basis component[J]. China Journal of Chinese Materia Medica, 2012, 37(14): 2181-2185 | |
| Authors: | SUN E JIA Xiaobin HUANG Yang CHEN Bin HU Qin XIAO Wei |
| Affiliation: | Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China;Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang 222001, China;Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China;Department of Pharmaceutics, Jiangsu University, Zhenjiang 212013, China;Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China;Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China;Department of Pharmaceutics, Jiangsu University, Zhenjiang 212013, China;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang 222001, China |
| Abstract: | To aim directly at the research status of Chinese drugs pharmaceutics, this study provides a new research idea "traditional Chinese medicine multiple drug delivery system based on material basis component". This thought according to whole concept, syndrome, and Chinese medicine characteristics of multi-component, multi-target, multi-effect. The premise of designing traditional Chinese medicine multiple drug delivery system is material basis component, and the purpose is to improve bioavailability. The example of multi-drug delivery system of tongmai micro-pellets is expounded for application. This new research model of Chinese drugs pharmaceutics provides new strategies and methods for the development of modern Chinese drug delivery systems. |
| Keywords: | traditional Chinese medicine multiple drug delivery system material basis component bioavailability Tongmai micro-pellets |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |