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诱导后MRSA与MSSA对万古霉素MIC差异分析
引用本文:代洪,范学工. 诱导后MRSA与MSSA对万古霉素MIC差异分析[J]. 湖南师范大学学报(医学版), 2011, 8(1): 34-36
作者姓名:代洪  范学工
作者单位:1. 中南大学湘雅医院传染科,湖南长沙410008;湖南师范大学医学院,湖南长沙410013
2. 中南大学湘雅医院传染科,湖南长沙,410008
摘    要:目的:分析万古霉素体外诱导后,MRSA与MSSA对万古霉素MIC有无差异.方法:在体外用万古霉素对15株金葡菌进行耐药诱导:诱导后比较MRSA与MSSA对万古霉素的MIC值.结果:有2株MRSA和1株MSSA对万古霉素产生中介耐药,诱导后MRSA与MSSA对万古霉素MIC均值无明显差异.结论:在体外诱导时MRSA与MS...

关 键 词:金黄色葡萄球菌  万古霉素  耐药

Studies on in-vitro induction of resistance in staphyloccus aureus to vancomycin and susceptibility of other antibiotics against vancomycin-resistantant staphyloccus aureus
Dai Hong,Fan Xuegong. Studies on in-vitro induction of resistance in staphyloccus aureus to vancomycin and susceptibility of other antibiotics against vancomycin-resistantant staphyloccus aureus[J]. Journal of Hunan Normal University(Medical Science), 2011, 8(1): 34-36
Authors:Dai Hong  Fan Xuegong
Affiliation:1(1.Department of Infectious Disease,Xiangya Hospital,Central South University,Changsha 410008,China; 2.Medical College,Hunan Normal University,Changsha 410006,China)
Abstract:Objective To analysis the differences of MIC to vancomycin between MRSA and MSSA.Methods 15 strains of S.aureus were cultured on BHI medium containing vancomycin and isolates were identified every 5 times of culture.The MIC to vancomycin of MRSA and MSSA were compared.Results 3 strains of vancomycin-intermediate resistance Staphylococcus aureus were gotten.The MIC values of vancomycin of MRSA and MSSA all increased after cultured with vancomycin Conclusion The in-vitro induction of fully resistance to vancomycin was very difficult.But there was no significant difference in MIC to vancomycin between MRSA and MSSA.
Keywords:Staphylococcus aureus  vancomycin  drug resistibility
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