| 诊断超声对大鼠胚胎脂质过氧化的近期和远期影响 |
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| 引用本文： | 王建宏,海春旭.诊断超声对大鼠胚胎脂质过氧化的近期和远期影响[J].中国超声医学杂志,1993,9(6):414-416. |
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| 作者姓名： | 王建宏 海春旭 |
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| 作者单位： | 第四军医大学西京医院超声科
(王建宏，钱蕴秋)，第四军医大学军队卫生教研室(海春旭) |
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| 摘 要： | 本文观察了诊断超声辐照对大鼠胚胎脂质过氧化（ＬＰＯ）的近期和远期影响。将孕１３日龄（１３ＧＤ）鼠胚胎持续宫内超声辐照３０分钟，分别于孕１４、１６、１８及２１日龄取鼠胚胎或胎肝组织测定ＬＰＯ各指标，并与同孕龄对照组进行比较。结果表明：超声辐照后孕１４日龄鼠胚胎组织ＭＤＡ含量增加（Ｐ〈０．０５），ＳＯＤ活性降低（Ｐ〈０．０５），我们认为与超声空化产生的自由基、脂质过氧化有关。而上述改变在超声辐照后７２
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| 关 键 词： | 超声生物效应 大鼠胚胎 过氧化脂质 |
Short and Long Term Effects of Diagnostic Ultrasound on Lipid Peroxidation of Rat Embryos |
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| Wang Jianhong,et al Xijing Hospital of Fourth Military Medical University.Short and Long Term Effects of Diagnostic Ultrasound on Lipid Peroxidation of Rat Embryos[J].Chinese Journal of Ultrasound in Medicine,1993,9(6):414-416. |
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| Authors: | Wang Jianhong Xijing Hospital of Fourth Military Medical University |
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| Abstract: | The short and long term effects of diagnostic ultrasound on lipid peroxidation (LPO) and antioxidation of rat embryos were studied in this article. The parameters of LPO were measured to observe the change trends of 14- , 16- , 18 -and 21 -GD rat embryos or fetuses exposed to diagnostic ultrasound for 30 minutes on the 13th day of gestation (13 -GD). The results showed that the MDA content increased (P<0. 05) and SOD activities decreased (P<0. 05) in 14-GD embryos tissue after exposure. These changes might be related to the free radical and LPO produced by ultrasound cavitation. However, the changes recovered to normal status in 16-GD fetuses (72 hours after exposure), it means that LPO changes faded away. |
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| Keywords: | Ultrasound biological effect Lipid peroxidation Rat embryos |
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