| Mitsunobu反应及其在药物化学中的应用 |
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| 引用本文： | 张庆文,周后元,尤启冬. Mitsunobu反应及其在药物化学中的应用[J]. 中国医药工业杂志, 2007, 38(10): 731-739 |
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| 作者姓名： | 张庆文 周后元 尤启冬 |
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| 作者单位： | 1. 上海医药工业研究院,上海,200437
2. 中国药科大学,江苏南京,210009 |
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| 摘 要： | 介绍了Mitsunobu反应的基本概况和研究新进展。举例说明了本反应在药物化学中的应用，重点放在药物及天然产物合成和构型反转上。
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| 关 键 词： | Mitsunobu反应 药物化学 应用 合成 综述 |
| 文章编号： | 1001-8255（2007）10-731-09 |
| 修稿时间： | 2007-04-12 |
Mitsunobu Reaction and Its Applications in Medicinal Chemistry |
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| ZHANG Qing-wen,ZHOU Hou-yuan,YOU Qi-dong. Mitsunobu Reaction and Its Applications in Medicinal Chemistry[J]. , 2007, 38(10): 731-739 |
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| Authors: | ZHANG Qing-wen ZHOU Hou-yuan YOU Qi-dong |
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| Affiliation: | 1. Shanghai Institute of Pharmaceutical Industry, Shanghai 200437; 2. China Pharmaceutical University, Nanjing 210009 |
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| Abstract: | This review deals with the general sketch and recent progress of Mitsunobu reaction, as well as its applications in medicinal chemistry with focus placed on synthesis and configuration inversion of drugs and natural products transformation. |
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| Keywords: | Mitsunobu reaction medicinal chemistry application synthesis review |
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