A fluorescence photographic photometric technique to assess stratum corneum turnover rate and barrier function in vivo |
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Authors: | AY FINLAY RJ MARSHALL R MARKS |
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Institution: | Department of Medicine, Welsh National School of Medicine, University Hospital of Wales, Heath Park, Cardiff;Department of Medical Illustration, University Hospital of Wales, Heath Park, Cardiff |
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Abstract: | A photographic photometric method for objective measurement of fluorescence in skin is described. This method has been used to (a) improve the dansyl chloride method for determining stratum corneum turnover time by making assessments objective and quantitative, and (b) examine the barrier function of the stratum corneum by measuring the concentration of a fluorescent material at different levels within the stratum corneum at different times. |
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