| 分子标志物在宫颈癌筛查中的应用 |
| |
| 引用本文： | 王静芳,郝敏. 分子标志物在宫颈癌筛查中的应用[J]. 中国妇幼健康研究, 2006, 17(3): 230-233 |
| |
| 作者姓名： | 王静芳 郝敏 |
| |
| 作者单位： | 山西医科大学第二医院妇产科,山西,太原,030001 |
| |
| 摘 要： | 宫颈癌在全球妇女恶性肿瘤中居第二位,在人乳头瘤病毒疫苗尚未在人群中应用之前,普查仍是预防和控制宫颈癌的主要手段.随着细胞分子生物学的研究进展,在细胞分子水平发现宫颈癌新的危险因素已成为当前研究热点.人乳头瘤病毒感染宫颈上皮细胞后所引起的一系列分子改变有可能作为人乳头瘤病毒感染的替代标志物,用于早期识别人乳头瘤病毒感染相关宫颈疾病.本文就目前所研究的有关宫颈疾病的诊断性分子标志物作以综述.
|
| 关 键 词： | 宫颈癌 分子标志物 诊断 筛查 |
| 文章编号： | 1673-5293（2006）03-0230-04 |
| 收稿时间： | 2006-04-03 |
| 修稿时间： | 2006-04-03 |
Application of molecular biomarkers in screening of cervical cancer |
| |
| WANG Jing-fang,HAO Min. Application of molecular biomarkers in screening of cervical cancer[J]. Chinese Journal of Maternal and Child Health Research, 2006, 17(3): 230-233 |
| |
| Authors: | WANG Jing-fang HAO Min |
| |
| Affiliation: | Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Shanxi Medical University, Shanxi Taiyuan 030001 ,China |
| |
| Abstract: | Cervical cancer is ranked the second place in female malignanciesworldwide.Screening is still the main measure in prevention and control of cervical cancer before HPV vaccines being widely applied to populations.With development of cell molecular biology,finding new risk factors of cervical cancer at molecule level has become the hotpoint of the study.A series of molecular changes after HPV infects the epithelial cells of cervix,may be as alternative biomarkers to be used to early identify those HPV associated cervical diseases.This article reviewed potential molecular biomarkers for diagnosis of cervical lesions in the recent researches. |
| |
| Keywords: | cervical cancer biomarker diagnosis screening |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
