Y-染色体单核苷酸多态性对中国黎族起源的研究

目的使用Y染色体单核苷酸多态性（Y—SNP）的证据从遗传学角度研究中国黎族的起源。方法选取部分与人类迁移相关的Y染色体非重组区的单核苷酸多态位点，采用PCR—RPLF和geno—typing法分析这些单核苷酸多态位点的多态性，观察由这些多态性位点组成的单倍型在黎族五个支系人群中的分布情况，并将结果与其他人群的分布进行比较。结果在黎族人群中发现4种Y染色体单倍型，其中单倍型O＊-175为五支系所共有，且分布频率都在95％以上，其它3个单倍型只在部分支系中很少量存在。结论黎族五个支系可能有共同的起源，起源于中国古代百越的可能性最大，并与台湾原住民关系非常接近。

Investigation into the origin of Li ethnic group in China by genetic analysis of Y chromosome single nucleotide polymorphism.

Objective To invesfiagte the origin of Li ethnic group in China by genetic analysis of Y - SNP. Methods Oligo nucleofide polymorphic sites on the noncombinatant part of Y chromosome associated with human nfigratinggenes were selected and the polymorphisms of the oligonucleotide on polynorphic sites were anlayzed by using CR - RPLF and geno - typing. The distribution of haplotype consisted of these polimorphic sites in the branches of five Li ethnic group was observed and the results were compared with other population. （6 biallelic markers located the nonrecombining portion of the Y chromosome in 335 males from 5 branches of Li ethnic groups, analysis the frequencies of Y - chromosome haplotype compared with several other East - Asia populations） . Results Four haplotypes were found in Li ethnic group in China, the O ＊ - M175 haplogroup was common and predominant in all branch groups, the other three were diversified. Conclusion The five branches of L/ ethnic groups aright be origined from the same ancestor and they might origined ancent Baiyue and are closely related with Malayan in Taiwan.