Crystalloid deposits in the kidney |
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Authors: | Keller Lisa Suzanne Faull Randall James Smith Peter Swift Jeffrey Bannister Kym Malcolm Otto Sophie Peh Chen Au |
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Institution: | Renal Unit, Royal Adelaide Hospital, North Terrace, Adelaide 5000, South Australia, Australia. |
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Abstract: | Light chain-producing lymphoproliferative disorders such as multiple myeloma are frequently complicated by renal impairment. Typically, the renal biopsy of a patient with renal failure caused by multiple myeloma shows cast nephropathy, but occasionally crystals may be seen. We describe the case of a patient with acute renal failure caused by multiple myeloma in which, on renal and bone marrow biopsy, there were widespread crystalloid deposits. Crystalloid nephropathy is a very rare condition associated with multiple myeloma and other light chain-secreting disorders. An underlying lymphoproliferative disorder should be considered in the differential diagnosis if crystalloid deposits are seen on a renal or other tissue biopsy. |
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Keywords: | crystalloid multiple myeloma nephropathy |
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