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Evaluation of Clonorchis sinensis Recombinant 7-Kilodalton Antigen for Serodiagnosis of Clonorchiasis |
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| Authors: | Qin-Ping Zhao Sung-Ung Moon Hyeong-Woo Lee Byoung-Kuk Na Seung-Yull Cho Yoon Kong Ming-Sen Jiang Ai-Hua Li and Tong-Soo Kim |
| Abstract: | The diagnostic applicability of the Clonorchis sinensis recombinant 7-kDa protein was evaluated. In enzyme-linked immunosorbent assays and immunoblots, the protein showed high sensitivities (81.3 and 71.9%, respectively) and specificities (92.6 and 89.7%, respectively) for sera obtained from various helminthic infections. Some paragonimiasis sera showed cross-reactions. The antigen might be valuable in the serodiagnosis of human clonorchiasis. |
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