低温透析在儿童血液透析中的应用

目的观察低温透析在儿童血液透析中的应用。方法选择首都医科大学附属北京儿童医院的急慢性透析患儿,分别进行常温透析（37℃）和低温透析（35℃）,共95人次。比较透析中血压、心率及低血压发生率的变化。结果在透析第3h低温透析组舒张压水平明显高于常温透析组（P=0.023）;与透析前基础血压相比,常温组舒张压和平均动脉压下降程度较低温组更显著,透析进行到第3h两组间均具有显著差异（分别为P=0.004和P=0.014）。在透析结束时,低温组具有稳定心率的优势,两组间有统计学意义（P=0.032）。在低血压发生率和透析效率方面无有统计学意义。结论低温透析在儿童中同样适用,可以有效维持透析中患儿血流动力学稳定。

The application of lower temperature dialysate for hemodialysis in children

Objective To observe the effect of lower temperature dialysate for hemodialysis in children.Methods We analyzed 95 times of hemodialysis using 37℃ dialysate or 35℃ dialysate for children with acute or chronic renal failure.Their blood pressure,heart rate and the incidence of hypotension were compared.Results After hemodialysis for 3 hours,the children treated with 35℃ dialysate showed higher diastolic blood pressure than those treated with 37℃ dialysate（P=0.023）.The decrease of diastolic and mean blood pressure was greater in children treated with 37℃ dialysate than in those with 35？ dialysate,and these differences became more apparent after the hemodialysis for 3 hours.In children treated with 35℃ dialysate,heart rate was relatively stable（P=0.032）,but without the advantages in hypotension incidence and dialysis efficiency.Conclusion Lower temperature hemodialysate is better in maintaining hemodynamic stability,and is also suitable for children.