Two mosaic-YY males carrying asymmetric Y chromosomes |
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| Authors: | L. Zelante B. Dallapiccola S. Calvano E. Memeo P. Gasparini P. Simi S. Rossi P. Finelli M. Rocchi N. Archidiacono |
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| Affiliation: | Servizio di Genetics Medica, IRCCS, Ospedale CSS San Giovanni Rotondo;Laboratorio di Citogenetica. Clinica Pediatrica, Universitàdi Pisa, Pisa;Istituto di Genetica, Universitàdi Bari, Bari, Italy |
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| Abstract: | Two patients were referred because of oligospermia and azospermia, respectively. Karyotypic analysis revealed two mosaic-YY males carrying asymmetric Y chromosomes. To our knowledge, no instance of double unequal Y chromosomes has been reported so far in human males. Results of fluorescent in situ hybridization (FISH) studies in spermatozoa from one of these patients revealed a significantly high number of hyperaploid spermatozoa. |
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| Keywords: | spermatogenesisyyyy Y chromosome |
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