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2006 consensus guidelines for the management of women with abnormal cervical cancer screening tests |
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| Authors: | Wright Thomas C Massad L Stewart Dunton Charles J Spitzer Mark Wilkinson Edward J Solomon Diane; American Society for Colposcopy and Cervical Pathology-sponsored Consensus Conference |
| Institution: | a Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, NY b Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO c Department of Obstetrics and Gynecology, Lankenau Hospital, Wynnewood, PA d Department of Obstetrics and Gynecology, Brookdale University Hospital and Medical Center, Brooklyn, NY e Department of Pathology, University of Florida College of Medicine, Gainesville, FL f National Institutes of Health and National Cancer Institute, Bethesda, MD. |
| Abstract: | A group of 146 experts representing 29 organizations and professional societies met September 18-19, 2006, in Bethesda, MD, to develop revised evidence-based, consensus guidelines for managing women with abnormal cervical cancer screening tests. Recommendations for managing atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion (LSIL) are essentially unchanged. Changes were made for managing these conditions in adolescents for whom cytological follow-up for 2 years was approved. Recommendations for managing high-grade squamous intraepithelial lesion (HSIL) and atypical glandular cells (AGC) also underwent only minor modifications. More emphasis is placed on immediate screen-and-treat approaches for HSIL. Human papillomavirus (HPV) testing is incorporated into the management of AGC after their initial evaluation with colposcopy and endometrial sampling. The 2004 Interim Guidance for HPV testing as an adjunct to cervical cytology for screening in women 30 years of age and older was formally adopted with only very minor modifications. |
| Keywords: | atypical squamous cells of undetermined significance cervical cancer screening cervical cytology high-grade squamous intraepithelial lesion human papillomavirus testing low-grade squamous intraepithelial lesion |
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