CAPD患者蛋白质丢失与腹透时间、PET及KT/Vurea的关系

对 16例新透析患者 (透析时间在 30d)和透析时间 >1年的 19例患者蛋白质丢失与透析时间、腹膜平衡试验 (PET)及尿素清除指数 (KT/Vurea)关系进行了分析。结果发现 :两组患者腹透液中 ,蛋白质丢失量比较差异无显著性 (P >0 .0 5 )。在PETD/Pcr值≥ 0 6 5患者腹透液中 ,蛋白质丢失量与PETD/Pcr值 <0 .6 5患者比较差异无显著性(P >0 .0 5 )。尿素清除指数 (KT/Vurea)≥ 2 0与KT/Vurea<2 0患者腹透液中蛋白质丢失量比较亦无统计学意义 (P >0 .0 5 )。提示 ,常规CAPD无腹膜炎患者腹透液中蛋白质丢失量与透析时间 ,小分子溶质转运 ,透析是否充分无相关性 ;进一步支持大分子蛋白质转运与小分子溶质转运可能为不同途径

Relationship between protein loss and dialysis duration results of PET and KT/V urea in CAPD patients

The study focused on the relationship between protein loss and dialysis duration, results of PET and KT/V urea in two groups of CAPD patients. 16 patients of one group were included in CAPD for only 30 days while 19 patients of the other group were included in CAPD for more than one year. The results showed that value of protein loss had no obvious significance between both groups. Compared with the patients with value of PET D/Pcr<0.65, the patients with value of PET D/Pcr≥0.65 had no significant protein loss. Between the patients whose index of urea clearance≥2.0, and those index of uera clearance <2.0 the protein loss had no difference. It is suggested that, in routine dialysis duration peritoneal transport of small solutes and dialysis adequency. The conclusion shows furtherly that transportion of large protein and small solutes through different ways.