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Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin |
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| Authors: | Dumitrescu Oana Boisset Sandrine Badiou Cedric Bes Michele Benito Yvonne Reverdy Marie-Elisabeth Vandenesch François Etienne Jerome Lina Gerard |
| Affiliation: | INSERM, U851, Lyon, France. |
| Abstract: | We examined the capacity of Staphylococcus aureus strains to release Panton-Valentine leukocidin (PVL) in the presence of antibiotics. No PVL was detected when S. aureus was incubated at inhibitory concentrations, while subinhibitory concentrations of oxacillin enhanced the PVL level; clindamycin, linezolid, and fusidic acid were inhibitory; and vancomycin had roughly no effect. |
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