| 适形调强放疗对鼻咽肿瘤退缩模式的影响 |
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| 引用本文： | 韩非,肖巍魏,王汉渝,黄莹,邓美玲,赵充,卢泰祥. 适形调强放疗对鼻咽肿瘤退缩模式的影响[J]. 中华放射医学与防护杂志, 2012, 32(2): 204-206 |
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| 作者姓名： | 韩非 肖巍魏 王汉渝 黄莹 邓美玲 赵充 卢泰祥 |
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| 作者单位： | 中山大学肿瘤防治中心放疗科华南肿瘤学国家重点实验室, 广州,510060 |
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| 摘 要： | 目的 回顾性分析适形调强放疗(IMRT)对鼻咽肿瘤退缩模式的影响.方法 选取2001年4月至2007年12月间接受单纯放疗初治鼻咽癌患者,其中,IMRT 196例,常规放疗76例.IMRT组照射总疗程平均为6周,常规放疗组总疗程平均为7周.结果 放疗结束时,IMRT组的鼻咽肿瘤和颈部淋巴结残留率分别为36.7％和44.2％,高于常规放疗组的21.1％和26.6％(x2=6.15和3.99,P＜0.05).放疗后3个月,IMRT组有6.1％残留,常规放疗组有9.2％残留,两组差异无统计学意义.IMRT组残留病灶在放疗后4～9个月时完全消退.结论 采用IMRT治疗初治鼻咽癌,肿瘤的退缩模式与常规放疗不同.IMRT结束时,肿瘤残留率较高,但只要靶区剂量充足,不宜盲目追加剂量.
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| 关 键 词： | 鼻咽癌 适形调强放疗 常规放疗 肿瘤退缩模式 放射生物效应 |
| 收稿时间： | 2011-08-26 |
Influence of intensity-modulated radiotherapy on tumor regression in nasopharyngeal carcinoma |
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| HAN Fei,XIAO Wei-wei,WANG Han-yu,HUANG Ying,DENG Mei-ling,ZHAO Chong and LU Tai-xiang. Influence of intensity-modulated radiotherapy on tumor regression in nasopharyngeal carcinoma[J]. Chinese Journal of Radiological Medicine and Protection, 2012, 32(2): 204-206 |
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| Authors: | HAN Fei XIAO Wei-wei WANG Han-yu HUANG Ying DENG Mei-ling ZHAO Chong LU Tai-xiang |
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| Affiliation: | Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, State Key Laboratory of Oncology in South China, Guangzhou 510060, China;Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, State Key Laboratory of Oncology in South China, Guangzhou 510060, China;Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, State Key Laboratory of Oncology in South China, Guangzhou 510060, China;Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, State Key Laboratory of Oncology in South China, Guangzhou 510060, China;Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, State Key Laboratory of Oncology in South China, Guangzhou 510060, China;Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, State Key Laboratory of Oncology in South China, Guangzhou 510060, China;Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, State Key Laboratory of Oncology in South China, Guangzhou 510060, China |
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| Abstract: | |
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| Keywords: | Nasopharyngeal carcinoma|Intensity-modulated radiotherapy|Conventional radiotherapy|Tumor regression mode|Radiation biology |
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