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白三烯受体拮抗剂对哮喘患者生存质量和气道炎症的作用
引用本文:邓星奇,廖晓寰,周亚刚,蔡映云,高育瑶,钱湘绮. 白三烯受体拮抗剂对哮喘患者生存质量和气道炎症的作用[J]. 中国组织工程研究与临床康复, 2002, 6(17): 2528-2529
作者姓名:邓星奇  廖晓寰  周亚刚  蔡映云  高育瑶  钱湘绮
作者单位:1. 复旦大学附属上海市第五人民医院(筹)上海,200240
2. 复旦大学附属中山医院,上海,200032
摘    要:目的探讨白三烯受体拮抗剂-扎鲁司特对成人哮喘患者生存质量和气道炎症的作用。方法40例哮喘患者随机分为治疗组和对照组各20例。治疗组口服扎鲁司特。对照组不用安可来。服药前及4周后采用成人哮喘生存质量评估表评估。并测定治疗前后气道炎症各指标水平。结果口服扎鲁司特4周后生存质量各因子分及总均分均有显著改善;气道炎症各指标均明显低于治疗前及对照组(P均<0.05)。结论扎鲁司特能改善哮喘患者的生存质量、抑制哮喘的气道炎症。

关 键 词:哮喘  白三烯受体拮抗剂  生存质量  气道炎症
文章编号:1671-5926(2002)17-2528-02
修稿时间:2002-03-05

The effect of leukotriene receptor a ntagonist on lung function,Q OL and airway inflammation in adults with asthma
DENG Xing-qi,LIAO Xiao-hua n,ZHOU Ya-gang,et al.. The effect of leukotriene receptor a ntagonist on lung function,Q OL and airway inflammation in adults with asthma[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2002, 6(17): 2528-2529
Authors:DENG Xing-qi  LIAO Xiao-hua n  ZHOU Ya-gang  et al.
Affiliation:DENG Xing-qi,LIAO Xiao-hua n,ZHOU Ya-gang,et al.The 5th People' s Hospital of Shanghai,Fudan Universi ty,Shanghai 200240,China
Abstract:Objective To explore the effect of za firlukast on the score of quality of life(QOL)and the airway inflammation in a dult s with asthma.Methods 40stable adults with asthma were assigned to two g roups.The zafirlukast group was treated with oral zafirluk ast which the contro l group wasn' t treated for 4weeks.Before and afte r experiment,the score of QOL were su rveyed,and indicator of airway inflammation were examined respectiv ely.Results Zafirlukast significantly improve d the score of QOL while decrease d the indicator of airway inflamma-tion.Conclusion Zafirlucast can effectively improv e the score of QOL,and curb the airway inflammation of asthma.
Keywords:s:asthma  leukotriene receptor antag onist  quality of life  airway infla mmati on
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