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Evaluation of the Lactate Threshold during Downhill Running in Rats
Authors:Wakako Tsumiyama  Sadaaki Oki  Namiko Umei  Michele Eisemann Shimizu  Takeya Ono  Akira Otsuka
Affiliation:1) Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan;2) Program in Biological System Sciences, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Japan;3) Department of Nursing and Rehabilitation, Konan Women’s University, Japan
Abstract:[Purpose] The purpose of the present study was to investigate if lactate thresholds inrats could be accurately determined during downhill running in rats. [Subjects]Twenty-four female Wistar rats were used in this study. Rats were randomly divided intotwo groups: the level running group and downhill running group. [Methods] Catheters wereinserted into the right external jugular veins of the rats. Two days after the operation,the rats performed incremental exercise tests. The level running group ran on a treadmillat a 0° incline; the downhill running group ran on a treadmill at a −16° incline. Thelactate threshold was determined using the 2-line combination that minimizes the total sumof squares for fitting all data. [Results] Maximal running speeds and running speeds atthe lactate threshold for the downhill running group were significantly higher than thosefor the level running group. [Conclusion] In this study, it was possible to accuratelydetermine the lactate threshold during downhill running. These findings suggest that whenthe treadmill speed is the same, downhill running can be done at lower metabolic intensitythan level running.Key words: Lactate threshold, Downhill running, Eccentric contraction
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