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New serological assay for detection of putative Helicobacter pylori virulence factors
Authors:Park Chang-Young  Cho Yong-Kyun  Kodama Tadashi  El-Zimaity Hala M T  Osato Michael S  Graham David Y  Yamaoka Yoshio
Institution:Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA.
Abstract:We evaluated a new immunoblot assay (Helicoblot 2.1) for Helicobacter pylori infection and CagA and VacA status by using serum samples from 222 patients. The test accurately detected H. pylori infection and VacA status, but improvements in the interpretation criteria are required before it can be recommended for determination of CagA status.
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