| 迷走神经刺激对缺血性心肌损伤保护作用的研究进展 |
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| 引用本文： | 张娟. 迷走神经刺激对缺血性心肌损伤保护作用的研究进展[J]. 国际病理科学与临床杂志, 2011, 31(1): 36-41. DOI: 10.3969/j.issn.1673-2588.2011.01.008 |
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| 作者姓名： | 张娟 |
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| 作者单位： | 上海交通大学医学院附属仁济医院麻醉科,上海,200127 |
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| 基金项目： | 国家自然科学基金(81001545)~~ |
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| 摘 要： | 缺血性心肌病是高病死率的常见疾病.研究表明,自主神经系统的功能与缺血性心肌病的发病及预后密切相关.在心肌缺血发生前后,给予迷走神经刺激能够显著减轻缺血造成的心肌损伤.本文重点讨论迷走神经刺激在缺血性心肌损伤方面的保护机制及其最新研究成果.
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| 关 键 词： | 迷走神经刺激 乙酰胆碱 心肌缺血 |
Advances in protective effects of vagal nerve stimulation against ischemia injury in myocardium |
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| ZHANG Juan. Advances in protective effects of vagal nerve stimulation against ischemia injury in myocardium[J]. Journal of International Pathology and Clinical Medicine, 2011, 31(1): 36-41. DOI: 10.3969/j.issn.1673-2588.2011.01.008 |
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| Authors: | ZHANG Juan |
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| Affiliation: | ZHANG Juan,WANG Xiangrui,SONG Jiangang (Department of Anesthesiology,Renji Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200127,China) |
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| Abstract: | Ischemic cardiomyopathy is a common disease with high morbidity and mortality.Extensive studies indicate that autonomic nervous activity has a significant role both in triggering myocardial ischemic events and modifying the clinical outcome.Vagal nerve stimulation,which is performed before or after myocardial ischemia,displays the protective effects against myocardial ischemic injury.This article summarized the advances of study on protective effects and mechanisms of vagal nerve stimulation against ischemi... |
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| Keywords: | vagal nerve stimulation acetylcholine myocardial ischemia |
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