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Efficacy and Safety of Immune Checkpoint Inhibitors in Patients with Microsatellite Instability-High End-Stage Cancers and Poor Performance Status Related to High Disease Burden |
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| Authors: | Filippo Pietrantonio Fotios Loupakis Giovanni Randon Alessandra Raimondi Massimiliano Salati Dario Trapani Filippo Pagani Ilaria Depetris Giulia Maddalena Federica Morano Salvatore Corallo Michele Prisciandaro Francesca Corti Vincenzo Guarini Alessandro Bocconi Antonio Marra Carmen Belli Andrea Spallanzani Matteo Fassan Sara Lonardi Giuseppe Curigliano Giovanni Fucà Maria Di Bartolomeo Filippo de Braud |
| Affiliation: | 1. Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy;2. Department of Oncology, Istituto Oncologico Veneto, IRCCS Padua, Italy;3. Department of Oncology and Hematology, University Hospital of Modena, Modena, Italy PhD Program in Clinical and Experimental Medicine, University of Modena and Reggio Emilia, Italy;4. New Drugs Development Division for Innovative Therapies, Istituto Europeo di Oncologia, IRCCS, Milan, Italy;5. Department of Oncology and Hematology, University Hospital of Modena, Modena, Italy;6. Surgical Pathology Unit, Department of Medicine, University of Padua, Padua, Italy;7. Oncology and Hemato-oncology Department, University of Milan, Italy New Drugs Development Division for Innovative Therapies, Istituto Europeo di Oncologia, IRCCS, Milan, Italy;8. Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy Oncology and Hemato-oncology Department, University of Milan, Italy |
| Abstract: | |
| Keywords: | Immune checkpoint inhibitors Microsatellite instability Mismatch repair deficiency Performance status Lazarus response |