坤泰胶囊联合芬吗通治疗女性绝经过渡期临床症状的研究

目的 研究坤泰胶囊联合芬吗通治疗绝经过渡期临床症状的疗效观察。方法 将100例绝经过渡期患者随机分为观察组50例和对照组50例，观察组给予坤泰胶囊联合芬吗通治疗，对照组仅给予芬吗通治疗，观察治疗前及治疗后3个月Kupperman评分、疗效对比、性激素浓度、骨密度的变化。结果 2组治疗3个月后K评分、FSH水平、LH水平均低于治疗前(P<0.05)，观察组治疗后改善程度显著低于对照组(P<0.05);2组治疗3个月后E₂水平、骨密度均高于治疗前(P<0.05)，观察组改善程度显著高于对照组(P<0.05)。结论 坤泰胶囊联合芬吗通能有效改善绝经过渡期的临床症状及骨质情况。

Studying Effect of Kuntai Capsule Treating Female Patients in Menopausal Transition Period Combined with Femoston

Objective To study the clinical effect of Kuntai capsule treating female patients in the menopausal transition period combined with femoston. Methods 100 menopausal patients were randomly divided into the control group and the observation group each with 50 person. Observation group received Kuntai capsule and femoston, the control group received femoston alone. The purpose is to test the changes in the score of clinical symptom, sex hormone concentration and bone density through standard of Kupperman and ultrasonic scan, etc. Results The Kupperman score, the level of FSH and LH in each group are both lower after 3 months treatment than before(P<0.05), and the level of FSH and LH in observation group is significantly lower than the control group (P<0.05). Level of E2 and bone density in observation group are massively higher than the control group after 3 months treatment(P<0.05). Conclusion Kuntai capsule combined with femoston can effectively relieve the clinical symptoms and bone condition during the menopausal transition period.