Endocrine functions in hypertensive rats of the NISAG strain exposed to epinephrine |
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| Authors: | G. S. Yakobson A. R. Antonov G. V. Petrova L. N. Maslova A. L. Markel' |
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| Affiliation: | (1) Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk;(2) Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk;(3) Medical Institute of the Ministry of Health and Medical Industry of the Russian Federation, Novosibirsk |
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| Abstract: | Endocrine functions were investigated in normotensive (Wistar) and hypertensive (NISAG) rats before and on days 3, 7, and 21 after subcutaneous epinephrine administration. Rats of the NISAG strain are characterized by elevated plasma levels of aldosterone and thyroxine and lowered plasma levels of immunoreactive insulin, and their endocrine system develops a much stronger response to a single epinephrine injection than does that of Wistar rats. This is manifested in a still higher aldosterone level, elevated corticosterone and insulin concentrations, and reduced thyroxine content in the plasma. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 5, pp. 495–498, May, 1996 |
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| Keywords: | hereditary arterial hypertension endocrine system response to epinephrine |
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