蒙脱石防治阿奇霉素所致胃肠道反应60例疗效观察

[目的]探讨蒙脱石对防治阿奇霉素所致胃肠道反应的疗效。[方法]将100例支原体肺炎、急性扁桃体炎患儿随机分为治疗组60例和对照组40例。两组均给予阿奇霉素,按体重5～10mg/kg,加入5%葡萄糖溶液100mL或250mL,同时加入维生素B_650～100mg,然后静脉滴注,滴注时间为2～3h,每日1次疗程均为5天。治疗组在治疗前半小时另加蒙脱石口服,每次2～3g,用温开水稀释摇匀后服下。观察两组治疗后胃肠道反应的情况。[结果]治疗组控制胃肠道反应的总有效率100%(60/60),对照组控制胃肠道反应的总有效率87.5%(35/40)。两组比较差异有统计学意义(均为P<0.05)。[结论]蒙脱石防治阿奇霉素所致胃肠道反应疗效确切。

The Montmorillonite Preventing and Controlling Arch Mildew Element Result Gastro-Intestinal Tract Responds 60 Example Curative Effect Observation

[Objective] To investigate the prevention and treatment of montmorillonite azithromycin reaction caused by the effect of the gastrointestinal tract. [Methods]100 cases of mycoplasma pneumonia in children with acute tonsillitis were randomly divided into treatment group 60 cases and 40 cases of the control group. Both groups were given azithromycin, according to the weight 5 ?10mg/kg, adding 5% glucose solution 100mL or 250mL, while adding vitamin B6 50 ~ 100mg, and then intravenous drip, drip of time for 2 ~3h, day 1 time course of 5 days. Treatment group in the treatment of the first half - hour oral plus montmorillonite, each 2 ~3g, diluted with warm water after the dose of shake. The two groups were observed after treatment of the situation in response to the gastrointestinal tract. [Results] The control treatment group the total response to the gastrointestinal tract and efficient 100% (60/60) , the control group to control the gastrointestinal tract of the total effective rate of response 87. 5% (35/40) . Difference between the two groups was statistically significant (all P <0.05) . [Conclusion] The prevention and treatment azithromycin montmorillonite gastrointestinal reaction induced by the exact effect.