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手性药物分析方法研究进展
引用本文:杨沐,钟文英,侯雯. 手性药物分析方法研究进展[J]. 药学进展, 2014, 0(3): 209-214
作者姓名:杨沐  钟文英  侯雯
作者单位:[1]中国药科大学分析化学教研室,江苏南京210009 [2]南京卡文迪许生物工程技术有限公司,江苏南京210033
摘    要:综述了近10年来手性药物分离检测方法的发展,包括高效液相色谱法、气相色谱法、毛细管电泳法,以及超临界流体色谱法等,旨在为该领域的进一步发展提供参考。

关 键 词:手性药物  手性分析  对映异构体

Advances in Research on Analytical Methods of Chiral Drugs
YANG Mu,ZHONG Wenying,HOU Wen. Advances in Research on Analytical Methods of Chiral Drugs[J]. Progress in Pharmaceutical Sciences, 2014, 0(3): 209-214
Authors:YANG Mu  ZHONG Wenying  HOU Wen
Affiliation:1. Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China; 2. Nanjing Cavendish Bio-Engineering Technology Co., Ltd., Nanjing 210033, China)
Abstract:The advances in research on methods of separation and detection for chiral drugs in recent ten years have been reviewed in this paper, including high performance liquid chromatography (HPLC), gas chromatography (GC), capillary electrophoresis (CE), supercritical fluid chromatography (SFC), etc.. All these may provide references for the further development of the analytical methods.
Keywords:hiral drug  chiral analysis  enantiomer
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