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Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib. |
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| Authors: | H G Hamzah A Pierce W A Stewart C Peter Downes A Gray A Irvine E Spooncer A D Whetton |
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